5-Amino-1MQ

5-Amino-1MQ Research Compound

Chemical Name: 5-Amino-1-methylquinolinium (commonly abbreviated 5-Amino-1MQ)
Synonyms: 5-amino-1-methylquinolinium, 5-A1MQ, NNMT inhibitor analog
CAS Number: 42464-96-0
Molecular Formula: C₁₀H₁₁N₂⁺ (monocationic quaternary ammonium)
Molecular Weight: ~159.21 g/mol (free cation); salts such as iodide forms ~286.11 g/mol

 Classification & Properties

• Classification: Synthetic small-molecule research compound; selective nicotinamide N-methyltransferase (NNMT) inhibitor

• Purity: ≥98–99% (HPLC-verified, research grade)

• Appearance: Off-white to pale yellow crystalline powder (salt) or reddish-brown to orange powder depending on form or salt

• Physical Form: Lyophilized or crystalline solid powder; may also be supplied in capsules or tablets depending on vendor

• Solubility: Soluble in water and dilute acids; also soluble in polar aprotic solvents such as DMSO

• Storage: Store desiccated and protected from light; long-term storage at –20 °C recommended

• Intended Use: For scientific research purposes only; not approved for human, clinical, or veterinary use

Available Dosages

• 10 mg, 20 mg (18 mg)

5-Amino-1MQ is a synthetic research compound studied for its ability to inhibit nicotinamide N-methyltransferase (NNMT). By influencing NAD⁺ activity, it provides scientists with a dependable tool for exploring energy balance, cellular pathways, and molecular regulation in controlled laboratory settings.

As an NNMT inhibitor, 5-Amino-1MQ allows researchers to observe how changes in NAD⁺ levels affect cellular function. Because NAD⁺ plays a central role in energy production and metabolic regulation, this compound is commonly used in studies focused on metabolism, cell signaling, and molecular resilience.

Each vial of 5-Amino-1MQ is supplied as a stable powder for laboratory use. Researchers typically reconstitute the powder prior to testing. To maintain compound integrity, it should be stored in a cool, dry location away from light. Once reconstituted, refrigeration is recommended, with long-term storage at –20 °C.

Key Benefits of 5-Amino-1MQ

• Supports research into enzyme inhibition

• Provides insights into NAD⁺ activity

• Useful for studies on energy balance

• Helps examine cellular regulation pathways

• Offers consistency in controlled laboratory testing

• Aids exploration of cellular resilience and function

• Delivered in a stable format for scientific research